VM2
VM2 is VeraChem's newest software package. Based upon a rigorous statistical thermodynamics framework, VM2 can provide accurate protein-ligand and host-guest binding free energies. It treats binding sites and ligands as fully flexible. A combination of rigorous conformational search algorithms with an energy model that includes solvation and entropic terms, make VM2 the most advanced end-point free energy method in routine use today. The latest version of VM2 is parallel processor enabled (MPI, OpenMP, CUDA).